Article

Patient-derived response estimates from zero-passage organoids of luminal breast cancer

2024-03-27

Abstract excerpt

<h4>Background: </h4> Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways specific to the luminal subtype. Breast cancer organoids are thought to retain tumor characteristics better, but long-term viability of luminal-subtype cases is a persistent challenge. Our goal was to adapt short-term organoi...

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Identifiers and source

Literature Corpus work: 770c99ef-262b-5e24-8062-249c3e6de9a6
DOI: 10.1101/2024.03.24.586432

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