Article

Bayesian and systems-level reanalysis of public tuberculosis progression transcriptomes reveals latent host-response programs

2026-03-19

Abstract excerpt

<title>Abstract</title> <p>Background Public tuberculosis progression transcriptomic datasets contain more biological information than can be captured by ranked-gene lists alone. We performed a systems-level reanalysis to assess latent structure, uncertainty-aware gene ranking, pathway convergence, and bias-sensitive interpretation in the harmonizable public cohorts. Methods Two cohorts with shared gene symbols...

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Literature Corpus work: 76ef168a-9db6-57a0-8702-991b7bcf6628
DOI: 10.21203/rs.3.rs-9154723/v1

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