Article

L-lactic acid induces short- and long-term cardioprotective effects through MCT1 transport, induction of metabolic reprogramming, and gene expression modulation

2024-11-06

Abstract excerpt

Lactic acid is recognized as an alternative fuel source for various tissues and is acknowledged for its protective effects in the brain. However, its potential as a cardioprotective agent remains controversial. Here, we aimed to (1) evaluate the impact of acute L-lactic acid administration, given at the onset of reperfusion, on myocardial infarct size in isolated mouse hearts submitted to transient global ischemia...

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Literature Corpus work: 76ed1471-e30f-5841-b26d-d93dd8fe8493
DOI: 10.1101/2024.11.05.621926

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