Article

Exploratory cross-cohort assessment of a post-hoc FAP-associated epithelial transcriptomic module in colorectal datasets

2026-08-28

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<title>Abstract</title> <p>Background Public transcriptomic reuse can test whether exploratory signals remain coherent across datasets, but post-hoc selection can create apparent reproducibility. We evaluated the evidence boundary of a locked 36-gene epithelial module generated after a negative donor-level screen in colorectal single-nucleus data containing paired familial adenomatous polyposis (FAP) samples. Me...

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Literature Corpus work: 76e0e913-cffd-511f-9876-bb42e23f3509
DOI: 10.21203/rs.3.rs-10669004/v1

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