Article

Characterization of a novel <i>Lbx1</i> mouse loss of function strain

2021-08-25

Abstract excerpt

Adolescent Idiopathic Scoliosis (AIS) is the most common type of spine deformity affecting 2-3% of the population worldwide. The etiology of this disease is still poorly understood. Several GWAS studies have identified single nucleotide polymorphisms (SNPs) located near the gene LBX1 that is significantly correlated with AIS risk. LBX1 is a transcription factor with roles in myocyte precursor migration, cardiac n...

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Literature Corpus work: 76d9b82e-062b-525b-b4ce-7f19792a8815
DOI: 10.1101/2021.08.25.457618

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