Article

Deletion of a conserved genomic region associated with adolescent idiopathic scoliosis leads to vertebral rotation in mice

2023-06-25

Abstract excerpt

<h4>ABSTRACT</h4> Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis, in which spinal curvature develops in adolescence, and 90% of patients are female. Scoliosis is a debilitating disease that often requires bracing or surgery in severe cases. AIS affects 2-5.2 percent of the population; however, the biological origin of the disease remains poorly understood. In this study, we aimed to de...

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Literature Corpus work: 7437b832-b7ea-5697-8ca3-5c5648b9e8f0
DOI: 10.1101/2023.06.22.546196

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