A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups.

doi:10.1136/jmedgenet-2013-102067

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Article

A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups.

Journal of medical genetics - 1 Jun 2014

Londono Douglas, Kou Ikuyo, Johnson Todd A, Sharma Swarkar, Ogura Yoji, Tsunoda Tatsuhiko, Takahashi Atsushi, Matsumoto Morio, Herring John A, Lam Tsz-Ping, Wang Xingyan, Tam Elisa M S, Song You-Qiang, Fan Yan-Hui, Chan Danny, Cheah Kathryn S E, Qiu Xusheng, Jiang Hua, Huang Dongsheng, TSRHC IS Clinical Group, International Consortium for Scoliosis Genetics, Su Peiqiang, Sham Pak, Cheung Kenneth M C, Luk Keith D K, Gordon Derek, Qiu Yong, Cheng Jack, Tang Nelson, Ikegawa Shiro, Wise Carol A

Abstract excerpt

BACKGROUND: Adolescent idiopathic scoliosis (AIS) is a common rotational deformity of the spine that presents in children worldwide, yet its etiology is poorly understood. Recent genome-wide association studies (GWAS) have identified a few candidate risk loci. One locus near the chromosome 10q24.31 LBX1 gene (OMIM #604255) was originally identified by a GWAS of Japanese subjects and replicated in additional Asian...

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Identifiers

PMID: 24721834
DOI: 10.1136/jmedgenet-2013-102067

Genes

LBX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups.PMID 24721834Read ↗

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