Article

Signals of polygenic adaptation on height have been overestimated due to uncorrected population structure in genome-wide association studies

2018-06-25

Abstract excerpt

Genetic predictions of height differ among human populations and these differences are too large to be explained by genetic drift. This observation has been interpreted as evidence of polygenic adaptation. Differences across populations were detected using SNPs genome-wide significantly associated with height, and many studies also found that the signals grew stronger when large numbers of subsignificant SNPs were...

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Literature Corpus work: 76af032f-500b-59f6-99b2-1866db7f52a4
DOI: 10.1101/355057

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