Article

Characterization of a lethal Crimean-Congo hemorrhagic fever virus infection model in interferon-deficient mice for studies of virus pathogenicity and vaccine’s efficacy

2025-12-23

Abstract excerpt

Crimean-Congo hemorrhagic fever virus (CCHFV) is a highly pathogenic tick-borne virus causing severe human disease and representing a significant public health threat. The absence of licensed vaccines and specific antiviral therapies highlights the need for well-characterized experimental models suitable for studying viral pathogenicity and evaluating medical countermeasures. In this study, we established and char...

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Literature Corpus work: 76991cc4-b0d3-5a99-add4-347a04849f95
DOI: 10.64898/2025.12.23.696184

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