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Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancer

2022-05-25

Abstract excerpt

<h4>Background: </h4> Combination chemotherapy has contributed to increased survival from Hodgkin disease (HD) and testicular cancer (TC). However, questions concerning the quality of spermatozoa after treatment have arisen. While studies have shown evidence of DNA damage and aneuploidy in spermatozoa years following anticancer treatment, the sperm epigenome has received little attention. Our objectives here were...

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Literature Corpus work
768a0eb9-c960-5857-92e1-1dfb21d33d94
DOI
10.21203/rs.3.rs-1665748/v1
Open publication

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Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancerDOI 10.21203/rs.3.rs-1665748/v1
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