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Article

Differential DNA Methylation Regions in Adult Human Sperm following Adolescent Chemotherapy: Potential for Epigenetic Inheritance.

PloS one - 1 Jan 2017

Shnorhavorian Margarett, Schwartz Stephen M, Stansfeld Barbara, Sadler-Riggleman Ingrid, Beck Daniel, Skinner Michael K

Abstract excerpt

BACKGROUND: The potential that adolescent chemotherapy can impact the epigenetic programming of the germ line to influence later life adult fertility and promote epigenetic inheritance was investigated. Previous studies have demonstrated a number of environmental exposures such as abnormal nutrition and toxicants can promote sperm epigenetic changes that impact offspring. METHODS: Adult males approximately ten...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28146567
DOI: 10.1371/journal.pone.0170085
PMCID: PMC5287489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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