Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic Alterations in Sperm DNA Associated with Testicular Cancer Treatment

10 Nov 2011

Abstract excerpt

DNA methylation, a key component of the epigenome involved in regulating gene expression, is initially acquired in the germ line at millions of sites across the genome. Altered sperm methylation patterns are associated with infertility and transgenerational effects in humans and rodents. Testicular cancer is the most common form of cancer among men of reproductive age and has a high cure rate associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22076425
DOI: 10.1093/toxsci/kfr307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Alterations in Sperm DNA Associated with Testicular Cancer TreatmentPMID 22076425Read ↗

Sperm DNA methylation dynamics after chemotherapy: a longitudinal study of a patient with testicular germ cell tumor treatmentSemantic proximity Read ↗

Epigenetics and Testicular Cancer: Bridging the Gap Between Fundamental Biology and Patient CareSemantic proximity Read ↗

Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancerSemantic proximity Read ↗

The Epigenetics of Testicular Germ Cell Tumors: Looking for Novel Disease BiomarkersSemantic proximity Read ↗

Unmasking the Epigenome: Insights into Testicular Cell Dynamics and Reproductive FunctionSemantic proximity Read ↗

Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancerSemantic proximity Read ↗

Recent Advancements in Research on DNA Methylation and Testicular Germ Cell Tumors: Unveiling the Intricate RelationshipSemantic proximity Read ↗

Epigenetic alterations in sperm associated with male infertilitySemantic proximity Read ↗

The dynamic epigenetic program in male germ cells: Its role in spermatogenesis, testis cancer, and its response to the environmentSemantic proximity Read ↗

Epigenetics and testicular germ cell tumorsSemantic proximity Read ↗

Epigenetic regulation in male germ cellsSemantic proximity Read ↗

The human sperm epigenome and its potential role in embryonic developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.