Article
PHARE: a bioinformatics pipeline for compositional profiling of multiclonal Plasmodium falciparum infections from long-read Nanopore sequencing data.
The Journal of antimicrobial chemotherapy - 2 May 2024
Hosch Salome, Wagner Philipp, Giger Johanna Nouria, Dubach Nina, Saavedra Elis, Perno Carlo Federico, Gody Jean-Chrysostome, Pagonendji Marilou Sonia, Ngoagouni Carine, Ndoua Christophe, Nsanzabana Christian, Vickos Ulrich, Daubenberger Claudia, Schindler Tobias
Abstract excerpt
BACKGROUND: The emergence of drug-resistant clones of Plasmodium falciparum is a major public health concern, and the ability to detect and track the spread of these clones is crucial for effective malaria control and treatment. However, in endemic settings, malaria infected people often carry multiple P. falciparum clones simultaneously making it likely to miss drug-resistant clones using traditional molecular...
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