Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome

30 Jun 2015

Abstract excerpt

Currently, very few prognosticators accurately predict metastasis in cancer patients. In order to complete the metastatic cascade and successfully colonize distant sites, carcinoma cells undergo dynamic epithelial-mesenchymal-transition (EMT) and its reversal, mesenchymal-epithelial-transition (MET). While EMT-centric signatures correlate with response to therapy, they are unable to predict metastatic outcome....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related Molecular Pathways
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26123483
DOI: 10.1038/srep11766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 28 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcomePMID 26123483Read ↗

Update on Epithelial-Mesenchymal Plasticity in Cancer ProgressionSemantic proximity Read ↗

Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticitySemantic proximity Read ↗

Lineage Plasticity: The New Cancer Hallmark on the Block.Semantic proximity Read ↗

Epithelial-Mesenchymal Transition—A Hallmark of Breast Cancer MetastasisSemantic proximity Read ↗

Maintenance of epithelial traits and resistance to mesenchymal reprogramming promote proliferation in metastatic breast cancerSemantic proximity Read ↗

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor ProgressionSemantic proximity Read ↗

EMT and MET: necessary or permissive for metastasis?Semantic proximity Read ↗

An epithelial-mesenchymal-amoeboid transition gene signature reveals subtypes of breast cancer progression and metastasisSemantic proximity Read ↗

Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis.Semantic proximity Read ↗

Transcriptomic-Based Quantification of the Epithelial-Hybrid-Mesenchymal Spectrum across Biological ContextsSemantic proximity Read ↗

Transcriptomic-based quantification of the epithelial-hybrid-mesenchymal spectrum across biological contextsSemantic proximity Read ↗

Stationed or Relocating: The Seesawing EMT/MET Determinants from Embryonic Development to Cancer MetastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.