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Disruption of c-MYC binding and chromosomal looping involving genetic variants associated with ankylosing spondylitis upstream of <i>RUNX3</i> promoter

2021-09-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Ankylosing Spondylitis (AS) is a common form of inflammatory spinal arthritis with a complex aetiology and high heritability, involving more than 100 genetic associations. These include several AS-associated single nucleotide polymorphisms (SNPs) upstream of RUNX3 , which encodes the multifunctional RUNT-related transcription factor (TF) 3. The lead associated SNP rs660024...

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Literature Corpus work
76411ae0-ae49-5ec9-beae-689e91fe52e2
DOI
10.1101/2021.09.07.459234
Open publication

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Disruption of c-MYC binding and chromosomal looping involving genetic variants associated with ankylosing spondylitis upstream of <i>RUNX3</i> promoterDOI 10.1101/2021.09.07.459234
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