Article

Bioprinting of Human Primary and iPSC-derived Islets with Retained and Comparable Functionality

2024-10-16

Abstract excerpt

Currently, Type 1 diabetes (T1D) can be treated through implantation of allogenic islets, which replenish the beta cell population, however this method requires an extensive post-implantation immunosuppressant regimen. Personalized cellular therapy can address this through implantation of an autologous cell population, induced pluripotent stem cells (iPSCs). Cellular therapy, however, requires an encapsulation dev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13fc0b9e-fd78-5cbe-a2b7-e421220707aa
DOI: 10.1101/2024.10.14.617656

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bioprinting of Human Primary and iPSC-derived Islets with Retained and Comparable FunctionalityDOI 10.1101/2024.10.14.617656Read

Recent Advances in the Development of Bioartificial Pancreas Using 3D Bioprinting for the Treatment of Type 1 Diabetes: A ReviewSemantic proximity Read

Adipose-derived stromal cells preserve pancreatic islet function in a transplantable 3D bioprinted scaffoldSemantic proximity Read

Towards 3D-Bioprinting of an Endocrine Pancreas: A Building-Block Concept for Bioartificial Insulin-Secreting TissueSemantic proximity Read

Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signallingSemantic proximity Read

Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In VivoSemantic proximity Read

Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling.Semantic proximity Read

Adherent reformed islets: a long-term primary cell-based platform for exploring mouse and human islet biologySemantic proximity Read

The functional performance of microencapsulated human pancreatic islet-derived precursor cells.Semantic proximity Read

Extended perfused culture of cm-scale endocrine pancreatic tissues created through sacrificial embedded printing into alginateSemantic proximity Read

Stem Cell Therapy for Diabetes: Beta Cells versus Pancreatic ProgenitorsSemantic proximity Read

Islet organoid as a promising model for diabetesSemantic proximity Read

The Current Status of Allogenic Islet Cell TransplantationSemantic proximity Read