Article

Computation of single-cell metabolite distributions using mixture models

2020-10-08

Abstract excerpt

Metabolic heterogeneity is widely recognised as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity may result from the inherent stochasticity of intracellular events. However, metabolism has been traditionally viewed as a purely deterministic process, on the basis that highly abundant metabolites tend to filter out stochastic phenomena...

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Literature Corpus work: 762d6ab2-4f17-50b5-b205-04710ef5211e
DOI: 10.1101/2020.10.07.329342

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