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Article

High throughput physiological screening of iPSC-derived cardiomyocytes for drug development.

Biochimica et biophysica acta - 1 Jul 2016

Del Álamo Juan C, Lemons Derek, Serrano Ricardo, Savchenko Alex, Cerignoli Fabio, Bodmer Rolf, Mercola Mark

Abstract excerpt

Cardiac drug discovery is hampered by the reliance on non-human animal and cellular models with inadequate throughput and physiological fidelity to accurately identify new targets and test novel therapeutic strategies. Similarly, adverse drug effects on the heart are challenging to model, contributing to costly failure of drugs during development and even after market launch. Human induced pluripotent stem cell...

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Identifiers

PMID: 26952934
DOI: 10.1016/j.bbamcr.2016.03.003
PMCID: PMC4885786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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