Article
Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes.
Circulation. Arrhythmia and electrophysiology - 1 Feb 2013
Lieu Deborah K, Fu Ji-Dong, Chiamvimonvat Nipavan, Tung Kelvin Chan, McNerney Gregory P, Huser Thomas, Keller Gordon, Kong Chi-Wing, Li Ronald A
Abstract excerpt
BACKGROUND: Human embryonic stem cells (hESCs) can be efficiently and reproducibly directed into cardiomyocytes (CMs) using stage-specific induction protocols. However, their functional properties and suitability for clinical and other applications have not been evaluated. METHODS AND RESULTS: Here we showed that CMs derived from multiple pluripotent human stem cell lines (hESC: H1, HES2) and types (induced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
