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Article

The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease.

Mechanisms of development - 1 Nov 2016

Sidhaye Jaydeep, Pinto Clyde Savio, Dharap Shweta, Jacob Tressa, Bhargava Shobha, Sonawane Mahendra

Abstract excerpt

Microvillus inclusion disease (MVID) is a life-threatening enteropathy characterised by malabsorption and incapacitating fluid loss due to chronic diarrhoea. Histological analysis has revealed that enterocytes in MVID patients exhibit reduction of microvilli, presence of microvillus inclusion bodies and intestinal villus atrophy, whereas genetic linkage analysis has identified mutations in myosin Vb gene as the...

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Identifiers

PMID: 27497746
DOI: 10.1016/j.mod.2016.08.001
PMCID: PMC5161235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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