Article
Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing
2024-02-21
Abstract excerpt
Medulloblastoma (MB) is one of the most common malignant brain tumors in children. Current preclinical in vivo model systems for MB have increased our understanding of molecular mechanisms regulating MB development; however, they may not be suitable for high-throughput screening efforts. We demonstrate here that transplantation of seven different MB cell lines or patient-derived cells into the blastula stage of z...
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Identifiers and source
- Literature Corpus work
- 75eec319-6c70-51ba-a696-cb5770b3991a
- DOI
- 10.1101/2024.02.21.578208