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Article

A Novel Zebrafish Xenotransplantation Model for Study of Glioma Stem Cell Invasion

16 Apr 2013

Abstract excerpt

Invasion and metastasis of solid tumors are the major causes of death in cancer patients. Cancer stem cells (CSCs) constitute a small fraction of tumor cell population, but play a critical role in tumor invasion and metastasis. The xenograft of tumor cells in immunodeficient mice is one of commonly used in vivo models to study the invasion and metastasis of cancer cells. However, this model is time-consuming and...

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PMID: 23613942
DOI: 10.1371/journal.pone.0061801

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