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Genetic evidence for a causal relationship between Alzheimer’s disease and age-related macular degeneration: A Mendelian randomization study

2024-02-02

Abstract excerpt

<h4>Background: </h4> Previous observational studies have established a bi-directional association between age-related macular degeneration (AMD) and Alzheimer’s disease (AD). However, these associations might be induced by confounding factors. Methods We conducted a bi-directional MR study to evaluate potential causal associations between AMD and AD using GWAS data. 39,106 clinically diagnosed AD cases, 46,828 p...

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Literature Corpus work
75e81b31-2d30-5e05-a472-ea2860c9c8a8
DOI
10.21203/rs.3.rs-3916453/v1
Open publication

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Genetic evidence for a causal relationship between Alzheimer’s disease and age-related macular degeneration: A Mendelian randomization studyDOI 10.21203/rs.3.rs-3916453/v1
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