Article
A pathway-centric view of spatial proximity in the 3D nucleome across cell lines
2015-09-17
Abstract excerpt
Spatial organization of the genome is critical for condition-specific gene expression. Previous studies have shown that functionally related genes tend to be spatially proximal. However, these studies have not been extended to multiple human cell types, and the extent to which context-specific spatial proximity of a pathway is related to its context-specific activity is not known. We report the first pathway-centr...
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Identifiers and source
- Literature Corpus work
- 75d0600c-d169-5b81-beeb-1c8559049be7
- DOI
- 10.1101/027045