Article

Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in <i>C. elegans</i>

2020-12-29

Abstract excerpt

<h4>Summary</h4> Understanding the molecular events that regulate cell pluripotency versus acquisition of differentiated somatic cell fate is fundamentally important. Studies in C. elegans demonstrate that knockout of the germline-specific translation repressor gld-1 , causes germ cells within tumorous gonads to form germline-derived teratoma. Previously we demonstrated that ER stress enhances this phenotype to...

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Literature Corpus work: 5f1daea5-9c68-5827-99dd-d8977f06a992
DOI: 10.1101/2020.12.29.424718

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