Article
Organ-specific rewiring of mitochondrial integrity through COX7A dictates cellular ploidy control
2025-09-30
Abstract excerpt
<h4>ABSTRACT</h4> To achieve proper cell and tissue size, cytoplasmic and nuclear growth must be coordinated. Disrupting this coordination causes birth defects and disease. In nature’s largest cells, nuclear growth occurs through polyploidization (whole-genome-duplication). How the massive nuclear growth of polyploid cells is coordinated with cytoplasmic growth processes such as mitochondrial biogenesis is relati...
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Identifiers and source
- Literature Corpus work
- 75b57573-9099-56f5-8d5e-74300a52911b
- DOI
- 10.1101/2025.09.29.678879