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Oxidative Stress in Shiga Toxin Production by Enterohemorrhagic Escherichia coli

20 Dec 2015

Abstract excerpt

Virulence of enterohemorrhagic Escherichia coli (EHEC) strains depends on production of Shiga toxins. These toxins are encoded in genomes of lambdoid bacteriophages (Shiga toxin-converting phages), present in EHEC cells as prophages. The genes coding for Shiga toxins are silent in lysogenic bacteria, and prophage induction is necessary for their efficient expression and toxin production. Under laboratory...

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PMID: 26798420
DOI: 10.1155/2016/3578368

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