Article

A Systems Pharmacology Model of Ageing Identifies Optimal Combination Therapies With Secondary Benefits on Weight Loss and Metabolic Health

2026-04-23

Abstract excerpt

<h4>Background: </h4> Ageing is a systems level biological process underlying the onset and progression of multiple chronic disorders. Rather than arising from a single pathway, age related decline reflects interacting disturbances in metabolic regulation, inflammation, nutrient sensing, cellular stress responses, and tissue repair. Although GLP1 receptor agonists, sodium glucose cotransporter2 inhibitors, metform...

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Literature Corpus work: 74e30875-b9f8-5b2b-a88a-6e5d2067bd94
DOI: 10.64898/2026.04.22.26351392

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