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A Randomized Clinical Trial of Metformin to Reduce Frailty in Older Adults with Glucose Intolerance

2026-07-28

Abstract excerpt

<h4>Importance</h4> Preclinical and human observational studies suggest that metformin may decrease age-related pathology, including frailty. <h4>Objective</h4> Determine whether metformin reduces frailty progression and biological age in older adults with glucose intolerance, a population at increased risk of becoming frail. <h4>Design, Setting and Participants</h4> Randomized, double-blind, placebo-controlled...

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Literature Corpus work
4282d1c1-c8cf-56cf-9970-a40f54ef1dde
DOI
10.64898/2026.07.27.26359055
Open publication

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A Randomized Clinical Trial of Metformin to Reduce Frailty in Older Adults with Glucose IntoleranceDOI 10.64898/2026.07.27.26359055
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