Article
IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease.
Immunology letters - 1 Oct 2016
Srenathan Ushani, Steel Kathryn, Taams Leonie S
Abstract excerpt
The pro-inflammatory cytokine interleukin-17A (IL-17) has been the subject of research by many groups worldwide. IL-17 expression is often associated with a specific subset of CD4+ T cells (the so-called Th17 cells); however various other immune cell subsets can also synthesise and express IL-17, including CD8+ T cells. Here we review recent data regarding the presence of IL-17+ CD8+ T cells (also known as Tc17...
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