Article
Regulation and function of proinflammatory TH17 cells.
Annals of the New York Academy of Sciences - 1 Nov 2008
Martinez Gustavo J, Nurieva Roza I, Yang Xuexian O, Dong Chen
Abstract excerpt
Naïve CD4(+) helper T (TH) cells, upon activation by antigen-presenting cells (APC), differentiate into different types of effector cells that are characterized by their distinct cytokine production profiles and immune regulatory functions. In addition to TH1 and TH2 cells, a third subset of effector TH cells has recently been described and termed TH17. Since their identification, TH17 cells have emerged as...
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