Article

Role of the PERK-eIF2α-CHOP signaling axis in mucosal barrier injury caused by ulcerative colitis

2022-02-24

Abstract excerpt

<title>Abstract</title> <p>The etiology and pathogenesis of ulcerative colitis (UC) remain unclear. Therefore, we observed the activation and transduction of the protein kinase RNA-like endoplasmic reticulum kinase (PERK)–eukaryotic initiation factor 2α (eIF2α)–C/EBP homologous protein (CHOP) signaling axis from the perspective of endoplasmic reticulum stress (ERS) and explored the pathogenesis of UC. Cell surviv...

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Literature Corpus work: 74894f93-3e6f-5af2-9620-b75e29df1de8
DOI: 10.21203/rs.3.rs-1377137/v1

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