Article

Extracellular ATP released from <i>Candida albicans</i> activates non-peptidergic neurons to augment host defense

2020-01-28

Abstract excerpt

Intestinal microbes release ATP to modulate local immune responses. Herein we demonstrates that Candida albicans , an opportunistic commensal fungus, also modulates immune responses via secretion of ATP. We found that ATP secretion from C. albicans varied between standard laboratory strains. A survey of eighty-nine clinical isolates revealed heterogeneity in ATP secretion, independent of growth kinetics and intr...

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Identifiers and source

Literature Corpus work: 7452ea5c-1078-5587-82aa-6c5f7e28d6f2
DOI: 10.1101/2020.01.27.921049

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