Article

<i>Candida albicans</i> filamentation does not require the cAMP-PKA pathway in vivo

2022-03-26

Abstract excerpt

Candida albicans is one of the most prevalent human fungal pathogens. Its ability to transition between budding yeast and filamentous morphological forms (pseudohyphae and hyphae) is tightly associated with its pathogenesis. Based on in vitro studies, the cAMP-Protein Kinase A (PKA) pathway is a key regulator of C. albicans morphogenesis. Using an intravital imaging approach, we investigated the role of the cAMP-...

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Literature Corpus work: a5602ed0-59d5-5e58-bcf7-44460b76424d
DOI: 10.1101/2022.03.25.485899

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