Article
The role of<i>Candida albicans</i>AP-1 protein against host derived ROS in in vivo models of infection
1 Jan 2013
Abstract excerpt
Candida albicans is a major fungal pathogen of humans, causing mucosal infections that are difficult to eliminate and systemic infections that are often lethal primarily due to defects in the host's innate status. Here we demonstrate the utility of Caenorhabditis elegans, a model host to study innate immunity, by exploring the role of reactive oxygen species (ROS) as a critical innate response against C. albicans...
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