Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila melanogaster as a model organism for Alzheimer’s disease

22 Nov 2013

Abstract excerpt

Drosophila melanogaster provides an important resource for in vivo modifier screens of neurodegenerative diseases. To study the underlying pathogenesis of Alzheimer's disease, fly models that address Tau or amyloid toxicity have been developed. Overexpression of human wild-type or mutant Tau causes age-dependent neurodegeneration, axonal transport defects and early death. Large-scale screens utilizing a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cholinesterase and Neurodegenerative Diseases
Share to Genetics, Aging, and Longevity in Model Organisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24267573
DOI: 10.1186/1750-1326-8-35

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila melanogaster as a model organism for Alzheimer’s diseasePMID 24267573Read ↗

Using Drosophila amyloid toxicity models to study Alzheimer's diseaseSemantic proximity Read ↗

Insights from Drosophila melanogaster model of Alzheimer s diseaseSemantic proximity Read ↗

Drosophila melanogaster: Deciphering Alzheimer's DiseaseSemantic proximity Read ↗

A study on the amyloid toxicity in Alzheimer’s disease model of APPL-Gal4 Drosophila eyeSemantic proximity Read ↗

Drosophila Models of Alzheimer's Amyloidosis: The Challenge of Dissecting the Complex Mechanisms of Toxicity of Amyloid-β 42Semantic proximity Read ↗

Drosophila Models of Alzheimer's Disease: Advances, Limits, and PerspectivesSemantic proximity Read ↗

Alzheimer's disease and tauopathy studies in flies and worms.Semantic proximity Read ↗

Transgenic Drosophila models of Alzheimer's disease and tauopathies.Semantic proximity Read ↗

Drosophila Models of Tauopathies: What Have We Learned?Semantic proximity Read ↗

Genetic Dissection of Alzheimer’s Disease Using Drosophila ModelsSemantic proximity Read ↗

Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects.Semantic proximity Read ↗

Alzheimer′s disease: the silver tsunami of the 21 <sup>st</sup> centurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.