Article

An Inflammatory Signature Associated with Genetic Predisposition to Acute Necrotizing Encephalopathy

2026-04-24

Abstract excerpt

<h4>Background</h4> Acute necrotizing encephalopathy (ANE) is a rare and severe neurologic complication of viral infection in children, thought to result from a hyperacute cytokine storm causing blood-brain barrier disruption and central nervous system injury. Despite characteristic clinical and radiologic features, ANE remains poorly understood at the molecular level, with no validated biomarkers or targeted the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b50e2e08-0583-57c1-aa8c-7ff6d403bbc2
DOI: 10.64898/2026.04.24.26350762

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An Inflammatory Signature Associated with Genetic Predisposition to Acute Necrotizing EncephalopathyDOI 10.64898/2026.04.24.26350762Read

Pediatric recurrent acute necrotizing encephalomyelitis, RANBP2 genotype and Sars-CoV-2 infection: Diagnosis, pathogenesis and targeted treatments from a case study.Semantic proximity Read

The interplay of infection and genetics in acute necrotizing encephalopathySemantic proximity Read

The seven enigmas of SARS-CoV-2: From the past to the futureSemantic proximity Read

Genetic Acute Necrotizing Encephalopathy Associated with RANBP2: Clinical and Therapeutic Implications in PediatricsSemantic proximity Read

Outcomes in influenza and RANBP2 mutation-associated acute necrotizing encephalopathy of childhood.Semantic proximity Read

Pathogenesis and Management of Acute Necrotizing Encephalopathy.Semantic proximity Read

Host Genetics and Antiviral Immune Responses in Adult Patients With Multisystem Inflammatory SyndromeSemantic proximity Read

Acute Necrotizing Encephalopathy: 2 Case Reports on RANBP2 MutationSemantic proximity Read

Biallelic <i>IRAK4</i> Variants Associated with Severe Neurological Autoinflammation: An Expansion of the Clinical PhenotypeSemantic proximity Read

A Rare Case of COVID-19 Related Acute Necrotizing Encephalopathy With the RANBP2 Mutation in a Pediatric Patient.Semantic proximity Read

MIS-C: A COVID-19-as sociated condition between hypoimmunity and hyperimmunitySemantic proximity Read

RANBP2 mutation in an Indian child with recurrent acute necrotizing encephalopathy.Semantic proximity Read