Article

Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events

2020-04-06

Abstract excerpt

Nucleotide excision repair is the primary DNA repair mechanism that removes bulky DNA adducts such as UV-induced pyrimidine dimers. Correspondingly, genome-wide mapping of nucleotide excision repair with eXcision Repair sequencing (XR-seq), provides comprehensive profiling of DNA damage repair. A number of XR-seq experiments at a variety of conditions for different damage types revealed heterogenous repair in the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 73d98a76-9bec-544d-88e1-e8d1a9dcdb71
DOI: 10.1101/2020.04.06.027201

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair eventsDOI 10.1101/2020.04.06.027201Read

DNA repair in species with extreme lifespan differencesSemantic proximity Read

Nucleotide excision repair hotspots and coldspots of UV-induced DNA damage in the human genomeSemantic proximity Read

High resolution mapping of modified DNA nucleobases using excision repair enzymes.Semantic proximity Read

Repair-mediated duplication by capture of proximal chromosomal DNA has shaped vertebrate genome evolution.Semantic proximity Read

Nucleotide excision repair in humansSemantic proximity Read

High-throughput characterization of transcription factors that modulate UV damage formation and repair at single-nucleotide resolution.Semantic proximity Read

Mouse lemur transcriptomic atlas informs primate genes, mutations, physiology, and diseaseSemantic proximity Read

RNA polymerase II is released from the DNA template during transcription-coupled repair in mammalian cellsSemantic proximity Read

DNA polymerase beta and mammalian base excision repair.Semantic proximity Read

Mouse Genomic Associations with <i>Ex Vivo</i> Sensitivity to Simulated Space RadiationSemantic proximity Read

Signatures in CRISPR Mutational Spectra Reveal Role and Interplay of Genes in DNA RepairSemantic proximity Read

Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypesSemantic proximity Read