Article

FUS Mutation Causes Lipid Metabolism Disorder in Skeletal Muscle Associated With ALS

2021-10-22

Abstract excerpt

<title>Abstract</title> <p>Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, characterized by the dysfunction of upper and lower motor neurons accompanied by muscle weakness and wasting. Recently, several studies on ALS patients and animal models implicated muscle intrinsic toxicity played a role in the disease progression with uncertain mechanisms. In this study, we explored the pos...

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Identifiers and source

Literature Corpus work: 739f349f-3070-5fdc-b463-730bb2366f47
DOI: 10.21203/rs.3.rs-992572/v1

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