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Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors

2019-01-20

Abstract excerpt

The interplay between the immune system and tumor progression is well recognized. However, current human breast cancer immunophenotyping studies are mostly focused on primary tumors with metastatic breast cancer lesions remaining largely understudied. To address this gap, we examined exome-capture RNA sequencing data from 50 primary breast tumors (PBTs) and their patient-matched metastatic tumors (METs) in brain,...

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Literature Corpus work
d982b997-b5b1-53bd-bda6-21f9f7b3f90d
DOI
10.1101/525071
Open publication

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Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumorsDOI 10.1101/525071
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