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Purified Zymogens Reveal Mechanisms of Snake Venom Metalloproteinase Auto-Activation

2025-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Snake venoms contain diverse mixtures of toxins that evolved to incapacitate prey, but in humans they cause extensive pathology following snakebite envenomation. In viper venom, some of the most potent toxins are the haemorrhagic and coagulopathic snake venom metalloproteinases (SVMPs). Because venoms contain a SVMP cocktail, and due to their cytotoxicity, SVMP characterizations have been hamper...

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Literature Corpus work
738118b0-35bc-552d-b2ba-6771045f1634
DOI
10.1101/2025.06.27.661748
Open publication

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Purified Zymogens Reveal Mechanisms of Snake Venom Metalloproteinase Auto-ActivationDOI 10.1101/2025.06.27.661748
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