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Chemical Biology for Understanding Matrix Metalloproteinase Function

30 Aug 2012

Abstract excerpt

The matrix metalloproteinase (MMP) family has long been associated with normal physiological processes such as embryonic implantation, tissue remodeling, organ development, and wound healing, as well as multiple aspects of cancer initiation and progression, osteoarthritis, inflammatory and vascular diseases, and neurodegenerative diseases. The development of chemically designed MMP probes has advanced our...

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PMID: 22933318
DOI: 10.1002/cbic.201200298

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