Article

Meningeal solitary fibrous tumor cell states phenocopy cerebral vascular development and homeostasis

2023-07-26

Abstract excerpt

<title>Abstract</title> <p>Meningeal solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that are associated with hematogenous metastasis, and the cell states and spatial transcriptomic architecture of SFTs are unknown. Here we use single-cell and spatial RNA sequencing to show SFTs are comprised of regionally distinct gene expression programs that resemble cerebral vascular development and homeostasis....

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Literature Corpus work: 73718f0b-5975-56b2-a10d-25cb316fa039
DOI: 10.21203/rs.3.rs-3164953/v1

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