Molecular description of meningeal solitary fibrous tumors/hemangiopericytomas compared to meningiomas: two completely separate entities

Abstract excerpt

<title>Abstract</title> <p>Introduction: Meningeal solitary fibrous tumors (SFT), like all SFT, are defined by NAB2-STAT6 fusion and share clinicopathologic similarities with meningiomas, the most frequent meningeal tumors. Our aim is to establish the molecular identity of meningeal SFT and seek molecular prognostic factors. <h4>Methods:</h4> RNA sequencing and whole exome sequencing (WES) were performed in STAT6...

Topics

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• Follow-Up Studies
• Gene Fusion
• Genetic Association Studies
• Head and Neck Neoplasms
• Meningeal Neoplasms
• Repressor Proteins
• Soft tissue tumor case studies
• STAT6 Transcription Factor

Identifiers and source

Literature Corpus work

15da63fe-4b80-5646-995c-82178164c844

DOI

10.21203/rs.3.rs-642486/v1