Article

The evolutionary genomics of CTCF binding and functional signatures in mouse

2020-01-01

Abstract excerpt

Genetic differences within and between species predominantly lie in the noncoding sequence of the regulatory regions of the genome whose function and significance largely remain poorly understood. Despite significant progress in the field of genomics and the rapid progress in sequencing methods and the subsequent explosion of genomic data, our understanding of the role of the non- coding genetic sequence in the re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 73683dc5-e4fa-5490-8e60-18804b6e7990
DOI: 10.17863/cam.59535

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The evolutionary genomics of CTCF binding and functional signatures in mouseDOI 10.17863/cam.59535Read

Genome-wide comparative analysis reveals human- mouse regulatory landscape and evolutionSemantic proximity Read

Conserved and species-specific transcription factor co-binding patterns drive divergent gene regulation in human and mouse.Semantic proximity Read

Initial sequencing and comparative analysis of the mouse genome.Semantic proximity Read

DNA methylation patterns of transcription factor binding regions characterize their functional and evolutionary contextsSemantic proximity Read

Mouse Genome Informatics (MGI): reflecting on 25 years.Semantic proximity Read

The Th1 cell regulatory circuitry is largely conserved between human and mouseSemantic proximity Read

Principles of regulatory information conservation between mouse and human.Semantic proximity Read

Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.Semantic proximity Read

Comparison of sequence variants in transcriptomic control regions across 17 mouse genomes.Semantic proximity Read

Quantifying Functional Conservation of Human and Mouse Regulatory Elements via FUNCODESemantic proximity Read

Enhanced Transcriptome Maps from Multiple Mouse Tissues Reveal Evolutionary Constraint in Gene Expression for Thousands of GenesSemantic proximity Read

The mouse genome sequence--the end of the tail, or just the beginning?Semantic proximity Read