Article

Scupa: Single-cell unified polarization assessment of immune cells using the single-cell foundation model

2024-08-19

Abstract excerpt

Immune cells undergo cytokine-driven polarization in respond to diverse stimuli. This process significantly modulates their transcriptional profiles and functional states. Although single-cell RNA sequencing (scRNA-seq) has advanced our understanding of immune responses across various diseases or conditions, currently there lacks a method to systematically examine cytokine effects and immune cell polarization. To...

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Literature Corpus work: 732b29ba-f932-5a1e-b30b-0a55acdb1d6a
DOI: 10.1101/2024.08.15.608093

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