Article

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by NuRD

2020-02-05

Abstract excerpt

Differentiation of mammalian pluripotent cells involves large-scale changes in transcription and, among the molecules that orchestrate these changes, chromatin remodellers are essential to initiate, establish and maintain a new gene regulatory network. The NuRD complex is a highly conserved chromatin remodeller which fine-tunes gene expression in embryonic stem cells. While the function of NuRD in mouse pluripoten...

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Literature Corpus work: 72e09356-d739-5866-aa46-98c009db6afd
DOI: 10.1101/2020.02.05.935544

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