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Extravillous trophoblast model shows generation of bioequivalent N-glycans can maintain immunological protection against natural killer cell cytotoxicity

2026-08-14

Abstract excerpt

Extravillous trophoblasts (EVTs) are a trophoblast subpopulation critical for feto-maternal tolerance during early pregnancy, primarily using HLA-G to exert immunomodulatory effect, and possessing N-glycomic profiles distinct from other trophoblast subpopulations. However, whether the N-glycosylation confers distinct immunological properties to EVTs remains poorly understood. To investigate this, we employed JEG-3...

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Literature Corpus work: 72c2fd71-7aaf-58d9-8366-7bf4486af83e
DOI: 10.64898/2026.08.09.743710

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