Article

Phenotypic Characterization the Townes Sickle Mice

2014-12-06

Abstract excerpt

Abstract The HbSS-Townes mouse model, developed in Dr. Tim Townes laboratory, University of Alabama, Birmingham (and kindly provided by him to our laboratory) were created on a mixed genetic background in which the murine adult α-globin genes were replaced with the human α-globin gene (genotype: Hba hα/hα) and the murine adult β-globin genes were replaced with human sickle βS- and fetal Aγ-globin gene fragments li...

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Literature Corpus work: 72bc9a63-b01f-55ce-9f34-1d9cfd526f8c
DOI: 10.1182/blood.v124.21.4916.4916

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