Article

<i>SLCO1B1</i> functional variants and statin-induced myopathy in people with recent genealogical ancestors from Africa: a population-based real-world study

2023-12-03

Abstract excerpt

<h4>Background</h4> Clinical pharmacogenetic implementation guidelines for statin therapy are derived from evidence of primarily Eurocentric study populations. Functional SLCO1B1 variants that are rare in these study populations have not been investigated as a determinant of statin myotoxicity and are thus missing from guideline inclusion. <h4>Objective</h4> Determine the relationship between candidate functio...

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Literature Corpus work: 7295f8c5-a99e-5ee3-910a-845937bc9c9c
DOI: 10.1101/2023.12.02.23299324

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